Question
Blood is flowing across a flat surface of a polymeric material coated with an anti-coagulant drug. Equilibrium studies show that the drug has an equilibrium
Blood is flowing across a flat surface of a polymeric material coated with an anti-coagulant drug. Equilibrium studies show that the drug has an equilibrium solubility of 100 mg/L of blood. The fluid adjacent the plate equilibrates quickly. Assume that the blood is travelling across the polymeric material with a free stream velocity of 40 cm/sec. the polymeric material has a length in the direction of flow of 30 cm. The diffusivity of the drug is 4.3xto^-6 cm2/sec. The viscosity of blood is 0.03 g/cm.s and the density of blood is 1.056 g/cm3. Find the following:
1. Distance at which the laminar boundary ends (Turbulence occurs at Re >= 300,000) 2. Thickness of the velocity and concentration boundary layers at the end of the polymeric material. 3. Local and average mass transfer coefficient at the end of the polymeric material. 4. The elution flux of the drug from the polymeric material (J) using average Km
Problem #3 (25 points): Blood is flowing across a flat surface of a polymeric material coated with an anti-coagulant drug. Equilibrium studies show that the drug has an equilibrium solubility of 100 mg/L of blood. The fluid adjacent the plate equilibrates quickly. Assume that the blood is travelling across the polymeric material with a free stream velocity of 40 cm/sec. the polymeric material has a length in the direction of flow of 30 cm. The diffusivity of the drug is 4.3 x 10 cm/sec. The viscosity of blood is 0.03 g/cms and the density of blood is 1.056 g/cm. Find the following: 1. Distance at which laminar boundary layer ends (Turbulence occurs at Re 2 300.000) 2. Thickness of the velocity and concentration boundary layers at the end of the polymeric material. 3. Local and average mass transfer coefficient at the end of the polymeric material. (Note: Average mass transfer coefficient = 2 Km) 4. The elution flux of the drug from the polymeric material (J) using average KmStep by Step Solution
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