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Can you elucidate the molecular mechanisms underlying immune cell activation and signaling pathways mediated by antigen recognition receptors such as the T cell receptor (TCR)

Can you elucidate the molecular mechanisms underlying immune cell activation and signaling pathways mediated by antigen recognition receptors such as the T cell receptor (TCR) and B cell receptor (BCR), including the roles of protein kinases, adaptor proteins, and transcription factors in regulating immune cell responses? 

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