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Consider a rectangular-shaped gel tablet of thickness 0.652cm, width of 1.0cm and depth of 1.0 cm loaded with the drug Dramamine. The edges of the
Consider a rectangular-shaped gel tablet of thickness 0.652cm, width of 1.0cm and depth of 1.0 cm loaded with the drug Dramamine. The edges of the gel tablet are sealed so that diffusion of Dramamine occurs only along the thickness of the gel tablet. The initial concentration of the drug Dramamine (solute A) in the gel (B) is 64.0mg/cm3, to provide a total drug dosage of 41.7mg. The concentration of the drug at the exposed surface of the tablet is maintained at zero to provide a constant sink for mass transfer. The diffusion coefficient of the drug in the gel is 3107cm2/s. a) Analytically determine an equation for the concentration profile of A within the gel. b) Using this solution, what is the residual concentration of drug in the center of the tablet after 96 hours? c) Compare this result to results obtained using concentration-time charts. Consider a rectangular-shaped gel tablet of thickness 0.652cm, width of 1.0cm and depth of 1.0 cm loaded with the drug Dramamine. The edges of the gel tablet are sealed so that diffusion of Dramamine occurs only along the thickness of the gel tablet. The initial concentration of the drug Dramamine (solute A) in the gel (B) is 64.0mg/cm3, to provide a total drug dosage of 41.7mg. The concentration of the drug at the exposed surface of the tablet is maintained at zero to provide a constant sink for mass transfer. The diffusion coefficient of the drug in the gel is 3107cm2/s. a) Analytically determine an equation for the concentration profile of A within the gel. b) Using this solution, what is the residual concentration of drug in the center of the tablet after 96 hours? c) Compare this result to results obtained using concentration-time charts
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