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Eye drops and nasal sprays must also be isotonic. If a non-isotonic solution is applied, it can cause stinging and burning sensation. A pharmacist must

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Eye drops and nasal sprays must also be isotonic. If a non-isotonic solution is applied, it can cause stinging and burning sensation. A pharmacist must compound a prescription for 10mL of 1.0%w/v chloramphenicol eye drops. The molar mass of chloramphenicol is 323.13g/mol. a. What would be the freezing point depression for a 1.0% solution of chloramphenicol in water? Assume a van't Hoff factor of 1 for chloramphenicol. Ans: 0.06C b. The remainder of the eye drop solution must be created from NaCl so the overall freezing point depression is 0.52. Subtract your answer from part a from 0.52 to get the Fp contributed by salt. c. Use the Fp from part b to calculate the grams of salt needed for the eye dropper solution. Ans: 0.071gNaCl

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