Genetic factors affect alcohol metabolism. Facial flushing is seen in around 50% of Asians and is due to a deficiency in which enzyme and the accumulation of which metabolite? Alcohol dehydrogenase is the enzyme and acetaldehyde is the metabolite Aldehyde dehydrogenase is the enzyme and acetic acid is the metabolite Aldehyde dehydrogenase is the enzyme and acetaldehyde is the metabolite Alcohol dehydrogenase is the enzyme and acetic acid is the metabolite