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Give examples of applied statistics problems of interest to you in which there are challenges in: (a) Generalizing from sample to population. (b) Generalizing from

Give examples of applied statistics problems of interest to you in which there are challenges in: 

(a) Generalizing from sample to population. 

(b) Generalizing from treatment to control group. 

(c) Generalizing from observed measurements to the underlying constructs of interest. Explain your answers.

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