Hey,

I need help with the following question from pharmacokinetics and pharmacodynamics, thank you!

The question:

Sketch what the graphs would look like for a) elimination rate versus steady-state concentration for linear and saturated elimination, b) unbound concentration versus total concentration for constant and saturated protein binding, and c) bioavailability versus administered dose for constant or saturated fraction absorbed. Be clear in your sketch and indicate which of the drawn lines represent linear and non-linear pharmacokinetics.

The answer should contain 3 graphs and each graph should contain 2 lines (like the description in a, b and c). Thank you!