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how do i figure out the ATP and ADP values to plug in ? please explain Strategy for Overcoming an Untavorable Roaction: ATP. Dependent Chernical

how do i figure out the ATP and ADP values to plug in ? please explain
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Strategy for Overcoming an Untavorable Roaction: ATP. Dependent Chernical Coupling The phosphorylation of glucose to glucose 6 -phosphate is the Initial step in the catabolism of qlucose. The dirnct phosphocylation af a. Calculate the equilibrium constant for this reaction at stin the rat hepatocyte, the phyniological concentrations of glucose and are maintained at approximately 4.8mM. What is the equilibrium concentration of glucose 6-phospbute obtained by the direct phosphorylation of ghucose by f? Does this reaction ropresent a reasonable metabolic step for the catabolism of glucose? Explnin. qn=RT in keq q1=Keq=eRo/Rt, e13.800315310=kq=4.7103 b. In principle at least, one way to increase the concentration of glucose 6-phosphate is to drive the equilibrium reaction to the right by increasing the intracellular concentrations of glucose and plAssuming a fixed concentration of at 4.8mh4 how high would the intracellular concentration of glucose have to be to give an equilibrium concentration of glucose 6-phosphate of 250M (the normal physiological concentration)? Would this route be physiologically reasonable, given that the maximum solubility of glucose is less than 1M ? keq=ABCD$gglucose+piglucose6-phospratekeq=glucase+piglucose6pros=(4.7103)(4.8102)250106250mm21010511m4.8nm4.8103 c. The phosphorylation of glucose in the cell is coupled to the hydrolysis of ATP; that is, part of the free energy of ATP hydrolysis is used to phosphorylate glucose: 16.7=008315310lnka

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