Question
Human serum albumin (HSA) has a molecular weight of 66,000 g/mol. One compartment contains a solution with HSA and the other compartment in the
Human serum albumin (HSA) has a molecular weight of 66,000 g/mol. One compartment contains a solution with HSA and the other compartment in the osmotic cell contains only an electrolyte solution. At a pH of 8 the net charge on HSA is -20. (a) The compartment that only has the electrolyte solution is maintained at a pH-8 with 1 M solution of NaOH. Find the concentration of Na+ and OH- in the HSA-containing compartment with a protein concentration of 40 mg/g-water. (b) What is the osmotic pressure at 298.15K in the cell in part (a)? (c) Compute the electrostatic potential difference between the two cells in part (a).
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General Chemistry Principles And Modern Applications
Authors: Ralph Petrucci, Jeffry Madura, F. Herring, Carey Bissonnette
11th Edition
0132931281, 978-0132931281
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