In preparation for a clinical trial to test a new drug to control hypertension, you conduct a pilot study with 10 volunteers to determine how much SBP can change over time if left untreated.After 4 weeks, you find a mean = 0.9 with a 95% CI -4.1 to 2.3. A reviewer stated that these results are meaningless because blood pressure cannot be negative. Do you agree or disagree with this reviewer and why.