Instructions

respond TO your peers in a substantive manner.

PLEASE RESPOND ON THE TWO QUESTION SEPARATELY explain it differently. PLEASE ANSWER THE QUESTION 1 AND 2 BASED ON YOUR THOUGHTS, IDEA OR COMMENTS. THANKYOU

1. Clostridium difficile infectionis a gram-positive bacterial gastrointestinal infection that causes colitis, an inflammation of the colon, and diarrhea (Na & Kelly, 2017). C. Diff can be acquired by taking antibiotics for more than a week. Consequently, these powerful medicines kill both harmful and good bacteria, leaving the gastrointestinal tract susceptible to C. Diff infections. C diff can also be transmitted by direct contact with objects, food, and surfaces contaminated with feces from someone infected.

According to the National Library of Medicine, probiotics are good bacteria found in yogurts or dietary supplements, recommended to prevent and treat C. diff (Goldenberg et al., 2017). It was also stated by Nobel Laureate Eli Metchnikoff, a Russian scientist, that replacing harmful microbes with good microbes found in probiotics can modify gut flora, making it helpful in treating C diff infection (Na & Kelly, 2017).

Meanwhile, in the case of our patient Jane, I would recommend using probiotics to aid her recovery from C diff infection, which most likely was afflicted by her antibiotic use. However, it is vital to determine the onset of infection and the patient's history before prescribing probiotics. Some probiotics are helpful against C diff, while others are ineffective. For instance,Saccharomyces boulardiiis a probiotic yeast used to treat and protect against C difficle-associated diarrhea (Na & Kelly, 2017). Nevertheless, I would recommend this probiotic to Jane, along with her antibiotics, to help restore her normal gut microbiome and treat her clostridium difficile infection.

2. After acquiring knowledge that the use of probiotics can help with treatment forC. diff, I would suggestto the health care provider that it can help aid in the recovery of the patient. I would suggest it because studies show that probiotics can reduce C. diff by as much as 50%, and by combining probiotics with prebiotics it improves growth and engraftment in the host(Mills et.al., 2018). In 2006 another study showed a66% reduction in C. diff related diarrhea inpatients who were consistently taking probiotics alongside antibiotics. I currently work in a gastroenterology office and our providers always suggest the use of probiotics as part of their regimen in improving the patients overall gut health.

Studies show that aside from probiotics reducing C. diff by 50%, prescribing antibiotics and pairing it with probiotics reduces antibiotic-associated diarrhea (Rodgers et al., 2013). One third of patients who are prescribed antibiotics developed AAD or antibiotic-associated diarrhea and 17% of cases are considered fatal (Rodgers et al., 2013). Incorporating probiotics with antibiotics can help replenish the natural state of the GI tract with nonpathogenic organisms (Rodgers et al., 2013).

Since there are different types of probiotics, for Jane I would recommend a probiotic that is both strain specific and disease specific for her specific condition (EJC et.al, 2018).Probiotics are found in certain foods, drinks and dietary supplements so I would tend to Jane's preference as well as effectiveness of the chosen probiotic to ensure its effectiveness. Since probiotics consist of living healthy bacteria, Jane can continue to use probiotics daily to maintain a healthy gut as well as assist in digestion.