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NEED HELP WITH 10 and 11 (2016 practice exam) 10. Use the axes provided below to answer questions 8A and B. (2 pts) A) Draw

NEED HELP WITH 10 and 11 (2016 practice exam)

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10. Use the axes provided below to answer questions 8A and B. (2 pts) A) Draw a curve depicting the inactivation of Nay channels as a function of holding voltage, where at -80 m V none of the channels are inactivated; at -40 mV 50% of the channels are inactivated, and at +20 m V all of the channels are inactivated. (0.5 pt) B) Now draw a curve depicting the activation properties of Nay channels resulting from membrane depolarization to increasing voltages. Here, depolarizing voltage steps to -60 m V do not activate any Nav channels, step to 0 mV activate 50% of channels, and steps to +40 mV activate 100% of channels. (0.5 pt) 100- -100 % of Na channels % of Na, channels not inactivated that get activated 50- -50 -80 -60 -40 -20 0 20 40 Membrane voltage (mV) C) Define a window current, and label the voltage range where it occurs in the graph. (0.5 pts each, 1 pt total) 11. Briefly describe how silent glutamatergic synapses become activated during long term potentiation, describing all of the key neurotransmitter receptors, kinases, and events that give rise to the process. (3 pts)

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