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Please I need to answer questions 1. Alpha-1 antitrypsin (A1AT) deficiency is an autosomal codominant disorder (this means you have to inherit the recessive allele

Please I need to answer questions

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1. Alpha-1 antitrypsin (A1AT) deficiency is an autosomal codominant disorder (this means you have to inherit the recessive allele from both parents to demonstrate the deficiency). Alpha-1 antitrypsin is a protein that controls neutrophil elastase (which is released by white blood cells when they fight infection). Neutrophil elastase can attack healthy cells, especially those of the lungs and liver, unless tightly controlled by alpha-1 antitrypsin. If there is a deficiency of alpha-1 antitrypsin, you can develop lung damage or cirrhosis of the liver. It is difficult to diagnose (and many people are un-diagnosed, or incorrectly diagnosed) because the lung damage symptoms are coincident with chronic obstructive pulmonary disorder. In a group of 5500 people tested for the particular alleles responsible, 2 people were found to have the recessive co-dominant alleles. The expectation for the North American population is that 1 person in 1500 will have A1AT deficiency. (2 pts) a) If you were going to test the hypothesis that the sample data is consistent with the expected incidence of A1AT deficiency, what would be the null and alternative hypotheses? (6 pts) b) What is the probability that someone has A1AT deficiency if they are tested for it, and the test is positive? (show your work) (3 pts) c) How do you interpret the probability that you found in part b

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