Please show formula and work than you

Using the data below, suppose we focus on the proportions of patients who show improvement. Is there a statistically significant difference in the proportions of patients who show improvement between treatments 1 and 2. Run the test at a 5% level of significance Symptoms No Effect Symptoms Improved Total Worsened Treatment 1 22 14 14 50 Treatment 2 14 15 21 50 Treatment 3 9 12 29 50