Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

please solve this problem Assume the response of our new drug is continuous and distributed normally with mean, 0, and known variance 1. Xi ~N(0,1)

please solve this problem

image text in transcribed
Assume the response of our new drug is continuous and distributed normally with mean, 0, and known variance 1. Xi ~N(0,1) Within 30 patients we see a mean response of 0.3. Assume we place a uniform prior on 0 Pr(0) = 1 for all 0. Questions: What is the posterior distribution of 0? What is the posterior probability that 0 is bigger than 0? There is a 95% probability that 0 is between _ and What is the predictive probability of success of a 100 patient Phase 3 trial with known variance 1? At the end of Phase 3 we will do a one sided t-test (0>0) and claim success if the p-value

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Income Tax Fundamentals 2013

Authors: Gerald E. Whittenburg, Martha Altus Buller, Steven L Gill

31st Edition

1111972516, 978-1285586618, 1285586611, 978-1285613109, 978-1111972516

More Books

Students also viewed these Mathematics questions