Answered step by step
Verified Expert Solution
Question
1 Approved Answer
Prebiotic chemistry is the study of matter associated with the natural environment before the advent of life on earth. Our best guess about primordial earth
Prebiotic chemistry is the study of matter associated with the natural environment before the advent of life on earth. Our best guess about primordial earth is that simple inorganic precursors, and a few simple organic compounds, were present ( H2O, NH3,HCN, CH3CN,CH2CHCN, NC-CN, H2CO, HCCCN). Although aldehydes and ketones were not abundant, they seem like compounds that could have been transiently produced en route to important biomolecules. To practice arrow pushing, answer the following questions about the formation of the imidazole ring in histidine. formamidine o-Erythrose imidazole-4-glycol L-Histidine Formamidine a. Using the simple organic and inorganic precursors above identify which molecules likely react to produce formamidine. b. Identify the most nucleophilic site on each molecule in part a. c. Indicate the orbitals involved in the most nucleophilic sites in part b. (i.e. n,,,,p, ) d. Identify the electrophilic site on each molecule in part a. e. Indicate the orbitals involved in the most electrophilic sites in part d. (i.e. n,,,p, ) f. Propose a reasonable arrow pushing mechanisms that produces formamidine from the precursors you identified in part a. { Note: please explicitly show all proton transfer steps. }
Step by Step Solution
There are 3 Steps involved in it
Step: 1
Get Instant Access to Expert-Tailored Solutions
See step-by-step solutions with expert insights and AI powered tools for academic success
Step: 2
Step: 3
Ace Your Homework with AI
Get the answers you need in no time with our AI-driven, step-by-step assistance
Get Started