Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

Prebiotic chemistry is the study of matter associated with the natural environment before the advent of life on earth. Our best guess about primordial earth

image text in transcribed

Prebiotic chemistry is the study of matter associated with the natural environment before the advent of life on earth. Our best guess about primordial earth is that simple inorganic precursors, and a few simple organic compounds, were present ( H2O, NH3,HCN, CH3CN,CH2CHCN, NC-CN, H2CO, HCCCN). Although aldehydes and ketones were not abundant, they seem like compounds that could have been transiently produced en route to important biomolecules. To practice arrow pushing, answer the following questions about the formation of the imidazole ring in histidine. formamidine o-Erythrose imidazole-4-glycol L-Histidine Formamidine a. Using the simple organic and inorganic precursors above identify which molecules likely react to produce formamidine. b. Identify the most nucleophilic site on each molecule in part a. c. Indicate the orbitals involved in the most nucleophilic sites in part b. (i.e. n,,,,p, ) d. Identify the electrophilic site on each molecule in part a. e. Indicate the orbitals involved in the most electrophilic sites in part d. (i.e. n,,,p, ) f. Propose a reasonable arrow pushing mechanisms that produces formamidine from the precursors you identified in part a. { Note: please explicitly show all proton transfer steps. }

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image_2

Step: 3

blur-text-image_3

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Fundamentals Of General Chemistry Volume 1

Authors: John E McMurry, Carl A. Hoeger, Virginia E. Peterson, David S Ballantine, Michael Miller

4th Edition

1256785083, 978-1256785088

More Books

Students also viewed these Chemistry questions

Question

How committed are you to this action on a scale of 110?

Answered: 1 week ago

Question

What non-verbal behaviour do they demonstrate?

Answered: 1 week ago

Question

What language do they use?

Answered: 1 week ago