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Question 3 The pressure (in kPa) in a capillary is given by p(x)=2.3-0.9x Where x is the distance along the capillary in mm. The

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Question 3 The pressure (in kPa) in a capillary is given by p(x)=2.3-0.9x Where x is the distance along the capillary in mm. The total length of the capillary is L = 1.5 mm. The concentrations of various molecules in the blood are listed in Table Q3. Table Q3: Molecule concentrations. Molecule Concentration [mmol/L] NaCl 115 Glucose 4.3 Blood Urea Nitrogen 4.2 (BUN) Albumin 0.75 The temperature in the body is 37C and the ideal gas constant is R = 8.314 J/kg.mol. The oncotic pressure in the interstitial tissue is 0.6 kPa, and the static pressure is 0. a) Find the oncotic pressure in the blood b) Find an expression for the Net Filtration Pressure, as a function of x. You may neglect the Excluded Volume and Gibbs-Donnan effects, but do not neglect the Staverman coefficient, c) If the mean NFP along the capillary is 0.232 Pa, estimate the Staverman coefficient d) If you have considered the Excluded Volume and Gibbs-Donnan effects, would this have increased, decreased or had no effect on your estimate of the Net Filtration Pressure. Explain your reasoning. (Note, you are not being asked to re-calculate the Net Filtration Pressure.)

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