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b) The folowing QSAR equation is related to the biological activity of a series of molecules HN log = -0.1227 - 0.400 +1.02MR-0.8 n=21, P=0.81, s=0.40 (1) Explain what all the terms mean (including n, and s) and deduce whether the equation is valid. What does the equation tell you about the kind of substituent X which would give the best activity. (ii) Given the following information which of the following substituents would give the highest predicted activity F CI 0.14 0.71 1.12 0.15 0.23 0.18 MR 0.92 6.03 13.94 (15 marks] b) The folowing QSAR equation is related to the biological activity of a series of molecules HN log = -0.1227 - 0.400 +1.02MR-0.8 n=21, P=0.81, s=0.40 (1) Explain what all the terms mean (including n, and s) and deduce whether the equation is valid. What does the equation tell you about the kind of substituent X which would give the best activity. (ii) Given the following information which of the following substituents would give the highest predicted activity F CI 0.14 0.71 1.12 0.15 0.23 0.18 MR 0.92 6.03 13.94 (15 marks]