Question
The active site of the serine protease chymotrypsin is shown schematically below. i) Use curly arrows to show how the enzyme achieves cleavage of the
The active site of the serine protease chymotrypsin is shown schematically below.
i) Use curly arrows to show how the enzyme achieves cleavage of the amide bond.
ii) The histidine side chain contains imidazole. Is imidazole aromatic? Explain your reasoning.
Asp (His) H-N (Ser EN EN H-O R N- R I.
Step by Step Solution
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Cleavage of the amide bond Chymotrypsin a serine protease enzyme plays a major role in the cleavag...
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Organic Chemistry
Authors: Francis A. Carey
4th edition
0072905018, 978-0072905014
