Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

The concentration in the blood resulting from a single dose of drug normally decreases with time as the drug is eliminated from the body.

The concentration in the blood resulting from a single dose of drug normally decreases with time as the drug is eliminated from the body. Doses may therefore need to be repeated periodically to keep the concentration from dropping below some particular level. One mode for the effect of repeated doses gives the residual concentration just before the (n+1)st dose as R, = C,e +Ce4 where C, the change in concentration achievable by a single dose (mg/mL), k =the elimination constant (h), and , time between the doses (h). See the figure below. G= C, + Coe"o C-1 RA R2 R = Coe kio Time (h) Concentration (mg/mL) A) Write R, in closed form as a single fraction, and find R= lim R. B) Calculate R, and R, for C, =1 mg/ml., k = 0.1h" and 1, = 10h. How good an estimate of R is R,? C) If k = 0.01h and t, = 10h, find the smallest n such that R, >(1/2)R. Use

Step by Step Solution

3.43 Rating (169 Votes )

There are 3 Steps involved in it

Step: 1

Answer Sel Grven that ... blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Elementary Statistics

Authors: Mario F. Triola

11th Edition

321500245, 321500243, 978-0321500243

More Books

Students also viewed these Accounting questions

Question

Every real number is either a/an number or a/an_______ number.

Answered: 1 week ago