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To measure the physical properties of cells, a piezoelectric probe is used. The force applied by the probe is compared against how much the cell
To measure the physical properties of cells, a piezoelectric probe is used. The force applied by the probe is compared against how much the cell deforms. If F is the force applied by the probe, and w is the distance it moves into the cell, then the stiffness of the cell can be calculated from the rate of change, dF/dw. Zhang et al. found that if F is measured in ?N and w in ?m then for a zebrafish embryo:F = 3 x 10?? w³- 4.4 x 10?³w² + 3.93w+0.221Calculate dF/dw for a sample when w= 100?m.
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