Use the following information to answer questions 2-3. In a prospective cohort study, 3,850 women aged 40-79 were followed for 10 years to estimate the risk of developing COPD with e-cigarette use. Data from the study are summarized below, stratified on use of e-cigarettes.

	COPD	No COPD	Total
E-cigarettes use	60	405	465
Negative for e-cigarette use	120	3,265	3,385
Total	180	3,670	3,850