7.86 Macular degeneration is the most common cause of blindness in people older than 60 years....

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7.86 ● Macular degeneration is the most common cause of blindness in people older than 60 years. One variable thought to be related to a type of inflammation associated with this disease is level of a substance called soluble Fas ligand (sFasL) in the blood.

The accompanying table contains representative data on x 5 sFasL level for 10 patients with age-related macular degeneration. These data are consistent with summary quantities and descriptions of the data given in the paper “Associations of Plasma-

Soluble Fas Ligand with Aging and Age-Related Macular Degeneration” (Investigative Ophthalmology & Visual Science [2008]: 1345–1349).

The authors of the paper noted that the distribution of sFasL level was skewed and recommended a cube-root transformation. The cube-root values and the normal scores for a sample size of 10 are also given in the accompanying table.

x Cube Root of x Normal Score 0.069 0.41 21.539 0.074 0.42 21.001 0.176 0.56 20.656 0.185 0.57 20.376 0.216 0.60 20.123 0.287 0.66 0.123 0.343 0.70 0.376 0.343 0.70 0.656 0.512 0.80 1.001 0.729 0.90 1.539

a. Construct a normal probability plot using the untransformed data.

b. Does the normal probability plot appear linear or curved?

c. Construct a normal probability plot using the transformed data. Does the normal probability plot appear more nearly linear than the plot for the untransformed data?

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Related Book For  book-img-for-question

Introduction To Statistics And Data Analysis

ISBN: 9781305445963

5th Edition

Authors: Roxy Peck, Chris Olsen, Jay L Devore

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