Xenical Capsules. In Example 11.4 on page 538, we stated that, based on standards set by the

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Xenical Capsules. In Example 11.4 on page 538, we stated that, based on standards set by the United States Pharmacopeia (USP), a standard deviation of Xenical capsule weights of less than 2 mg is acceptable. We now ask you to obtain that result. In doing so, we presume that weights of Xenical capsules are normally distributed with a mean of 120 mg.

a. According to USP, the requirements for weight variation of capsules are met if each of the individual weights is within the limits of 90% and 110% of the mean weight. Find the lower and upper weight limits in order for USP requirements to be met.

b. Using statistical software, find the percentage of all possible observations of a normally distributed variable that lie within six standard deviations to either side of the mean.

c. Show that, if σ < 2, then fewer than two of every billion Xenical capsules will have weights that violate USP requirements. (Hint:

First determine the value of σ for which six standard deviations to either side of the mean give the lower and upper weight limits for USP requirements to be met.)

d. Explain why a standard deviation of Xenical capsule weights of less than 2 mg is reasonably acceptable with respect to USP requirements.

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Introductory Statistics

ISBN: 9781292099729

10th Global Edition

Authors: Neil A. Weiss

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