Oncogenes sometimes result from genetic rearrangements (e.g., translocations) that produce gene fusions. An example occurs in a

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Oncogenes sometimes result from genetic rearrangements (e.g., translocations) that produce gene fusions. An example occurs in a Philadelphia chromosome, in which a reciprocal translocation between chromosomes 9 and 22 leads to fusion of the first part of the bcr gene with the abl gene. Suggest two different reasons why a gene fusion can create an oncogene.


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