A mutation that changes an alanine residue in a protein to an isoleucine leads to a loss

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A mutation that changes an alanine residue in a protein to an isoleucine leads to a loss of activity. Activity is regained when a further mutation at the same site changes the isoleucine to a glycine. Why?

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Biochemistry

ISBN: 978-1285429106

8th edition

Authors: Mary K. Campbell, Shawn O. Farrell

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Question Posted: Jul 08, 2015 12:13 PM

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A mutation that changes an alanine residue in a protein to an isoleucine leads to a loss

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When alanine is replaced by isoleucine there is not enough room in the nati...View the full answer

Biochemistry

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