In the variant hemoglobin C, glutamate at position 6 of the chain has been replaced with

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In the variant hemoglobin C, glutamate at position 6 of the β chain has been replaced with lysine.
(a) Would you expect this mutant hemoglobin to polymerize as hemoglobin S does?
(b) Red blood cells containing hemoglobin C have a shorter lifespan than red blood cells containing normal hemoglobin. How might this affect a person's resistance to malaria?
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Fundamentals of biochemistry Life at the Molecular Level

ISBN: 978-0470547847

4th edition

Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt

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