FADH 2 is produced in the citric acid cycle by 4 a membrane-embedded enzyme complex, called succinate

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FADH2 is produced in the citric acid cycle by 4 a membrane-embedded enzyme complex, called succinate dehydrogenase, that contains bound FAD and carries out the reactions


succinate + FAD → fumarate + FADH2 and FADH2 → FAD + 2H+ + 2e


The redox potential of FADH2, however, is only –220 mV. Referring to Panel 14–1 and Figure 14–22, suggest a plausible mechanism by which its electrons could be fed into the electron-transport chain. Draw  diagram to illustrate your proposed mechanism.


Panel 14–1


image




Figure 14–22image

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Essential Cell Biology

ISBN: 9780393680362

5th Edition

Authors: Bruce Alberts, Karen Hopkin, Alexander Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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