Describe how each of the amino acid modifications shown in Fig. 4-14 would affect the pI of a peptide containing that modified amino acid residue.

Figure 4-14

Transcribed Image Text:

-PO- CH NH-CH-CO O-Phosphoserine 2 N1 3 5. N 4 -OOC CH CH -NH-CH-CO- y-Carboxyglutamate CH3 COO- CH -NH-CH-CO 3-Methylhistidine H OH 5 N-CH 2 3 1 COO- 4-Hydroxyproline i || HN-C-CH3 T CH CH CH CH -NH-CH-CO E-N-Acetyllysine