Ritonavir, an inhibitor of HIV protease (Box 12-3), also inhibits the chymotrypsin-like activity of the proteasome. Explain

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Ritonavir, an inhibitor of HIV protease (Box 12-3), also inhibits the chymotrypsin-like activity of the proteasome. Explain why this dual inhibitory effect could contribute to the neurotoxic side effects of long term ritonavir use.

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Fundamentals Of Biochemistry Life At The Molecular Level

ISBN: 9781118918401

5th Edition

Authors: Donald Voet, Judith G Voet, Charlotte W Pratt

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Question Posted: Oct 08, 2023 01:11 AM

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Ritonavir, an inhibitor of HIV protease (Box 12-3), also inhibits the chymotrypsin-like activity of the proteasome. Explain

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The proteasome is a multiprotein complex that degrades damaged or unneeded proteins in the cell It i...View the full answer

Fundamentals Of Biochemistry Life At The Molecular Level

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