Consider theshiftedmultiplicativePoissonmodelinthecasewhere r = s = 2. Showthatthelikelihoodequationsareequivalenttothefollowingequa- tion in : with expressingthattheestimatedcross-productratioisequaltothecross-productratio of thebackgroundrisk B. Usethistogiveanexplicitformulaforthemaximum

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Consider theshiftedmultiplicativePoissonmodelinthecasewhere r = s = 2. Showthatthelikelihoodequationsareequivalenttothefollowingequa-

tion in ρ:

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with

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expressingthattheestimatedcross-productratioisequaltothecross-productratio of thebackgroundrisk B. Usethistogiveanexplicitformulaforthemaximum likelihoodestimatorˆλ of λ in thisspecialcase.

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