A ligand binds two different receptors with a K d value of 10 -7 M for receptor

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A ligand binds two different receptors with a Kd value of 10-7 M for receptor l and a Kd value of 10-9 M for receptor 2. For which receptor does the ligand show the greater affinity? Calculate the fraction of receptors that have a bound ligand (IRL] / Rr) in the case of receptor 1 and receptor 2 if the concentration of free ligand is 10-8 M.

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Molecular Cell Biology

ISBN: 978-1429234139

7th edition

Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott

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