Calculate the G for the reaction of acetyl phosphate with CoASH, given that the G for the
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Calculate the ΔG°´ for the reaction of acetyl phosphate with CoA—SH, given that the ΔG°´ for the hydrolysis of acetyl phosphate is 243.1 kJ mol–1 (210.3 kcal mol–1) and the ΔG°´ for the hydrolysis of acetyl-CoA is 231.4 kJ mol–1 (27.52 kcal mol–1). As part of your calculation, draw a free-energy diagram relating the ΔG°´ of the two hydrolysis reactions to the DG°´ of the reaction between acetyl phosphate and acetyl-CoA.
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