The pK a of the thiol group of CoASH is 9.6. How would the DG for the
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The pKa of the thiol group of CoASH is 9.6. How would the DG° for the hydrolysis of acetyl-CoA change (relative to its value at pH = 7) if the hydrolysis were carried out at pH = 11? Explain.
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At pH 7 the thiol group should be about 100 protonated as discussed on text p 107 The pH is much low...View the full answer
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