When tert-butyl alcohol is treated with H 2 18 O (water containing the heavy oxygen isotope 18

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When tert-butyl alcohol is treated with H218O (water containing the heavy oxygen isotope 18O) in the presence of a small amount of acid, and the tert-butyl alcohol is re-isolated, it is found to contain 18O. Write a curvedarrow mechanism consisting of Brønsted acid–base reactions, Lewis acid–base associations, and Lewis acid–base dissociations that explains how the isotope is incorporated into the alcohol.

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Organic Chemistry

ISBN: 9781936221349

6th Edition

Authors: Marc Loudon, Jim Parise

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