Question: The following compound has one aldehyde group and two OH groups: Under acidic conditions, either one of the OH groups can function as a nucleophile
The following compound has one aldehyde group and two OH groups: Under acidic conditions, either one of the OH groups can function as a nucleophile and attack the carbonyl group, giving rise to two possible ring sizes.
(a) Ignoring stereochemistry (for now), draw both possible rings.
(b) In Section 4.9, we discussed the ring strain associated with different size rings. Based on those concepts, predict which cyclic hemiacetal will be favored in this case.

H.
Step by Step Solution
3.40 Rating (156 Votes )
There are 3 Steps involved in it
a b The sixmembered ring ... View full answer
Get step-by-step solutions from verified subject matter experts
Document Format (2 attachments)
1625_606b0df1d2324_662335.pdf
180 KBs PDF File
1625_606b0df1d2324_662335.docx
120 KBs Word File
