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12. How does the difference in stereochemistry between these two starting materials affect the type of products formed from this reaction. Draw the major elimination

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12. How does the difference in stereochemistry between these two starting materials affect the type of products formed from this reaction. Draw the major elimination product expected in each case and explain why it is the major one. CH(CH3)2 CI KH DMSO CH(CH3)2 CI KH DMSO 13. The following reaction occurs via an E2 mechanism, in which an alkene (II) is formed via a B- elimination reaction of the bromine in I. The stereochemistry of the product is not shown, but one alkene stereoisomer does predominate in this reaction. Ph. KO/Bu DMF OCH.CH Ph-C=CHCH CHE OCH CHE 1 II a) Draw a Newman projection (or a comparable drawing which clearly indicates conformation) of the reactive conformation of I. b) Using the information from (a), determine the stereoisomer of the alkene (II) that results from this reaction and draw it in the box below. Br c) HC Br2 H2O H3C + enantiomer + HBO HO While writing the mechanism, justify both the regiochemistry and the relative stereochemistry shown here. Make sure that you understand these terms

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