56. Match the following of the drugs with their correct Trade names.
i. Secobarbital A. Mustine
ii. Mechlorethamine B. Ipamide
iii. Cyclophosphamide C. Saconal
iv. Ifosfamide D. Cycloxan
a) i-B, ii-C, iii-D, iv-A
b) i-B, ii-C, iii-A, iv-D
c) i-C, ii-A, iii-D, iv-B
d) i-A, ii-D, iii-B, iv-C

57. Effect produced due to binding of secobarbital with GABAA receptor??
a) Increase in GABA affinity for GABA receptor
b) Decrease in GABA affinity for GABA receptor
c) Blocking of GABA receptor for GABA
d) None of the above

58. Esterification of either of the 1,3-diazine nitrogens of secobarbital results in?
a) Decrease in hypnotic activity
b) Increase in hypnotic activity
c) Bioavailability increases
d) Bioavailability decreases

59. Type/s of ring present in the structure of secobarbital?

I. Pyrimidine
II. Indole
III. Benzene
a) II, III
b) I, II
c) I
d) I, II, III

60. Side effect of drug Secobarbital?
a) Insomnia
b) Dizziness
c) Loss of coordination
d) All of the above

61. Match the following with correct SAR of the drug Flurazepami.
An electronegative group at 7-position of the ringA
A. Increases the functionalanxiolytic activity
ii. Substitutions at 6, 8 or 9 position withelectronegative group on ring A
B. Decreases the functionalanxiolytic activity.
C. Decrease the functionalanxiolytic activity
D. Increase the functionalanxiolytic activity
a) i-A, ii-D
b) i-A, ii-C
c) i-B, ii-C
d) i-B, ii-D