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6.61 Strychnine (6), a notorious poison isolated from the strychnos genus, is commonly used as a pesticide in the treatment infestations. The sophisticated structure of

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6.61 Strychnine (6), a notorious poison isolated from the strychnos genus, is commonly used as a pesticide in the treatment infestations. The sophisticated structure of strychnine, first elucidated in 1946, served as a tantalizing goal for synthetic organic chemists. The first synthesis of strychnine was achieved by R. B. Woodward (Harvard Univ.) in 1954 (J. Am. Chem. Soc. 1954, 76, 4749-4751). In the last step of Woodward's synthesis, 1 was converted into 6 via intermediates 2-5, as shown:

6.61a: Identify the sequence of arrow-pushing patterns

Strychnine (6), a notorious poison isolated from the Strychnos genus, is commonly used as a pesticide in the treatment of rodent infestations. The sophisticated structure of strychnine, first elucidated in 1946 , served as a tantalizing goal for synthetic organic chemists. The first synthesis of strychnine was achieved by R. B. Woodward (Harvard Univ.) in 1954 (J. Am. Chem. Soc. 1954, 76, 47494751). In the last step of Woodward's synthesis, 1 was converted into 6 via intermediates 25, as shown: OH OH Identify the sequence of arrow-pushing patterns. Conversion of 1 to 2 is a Conversion of 2 to 3 is a Conversion of 3 to 4 is a Conversion of 4 to 5 is a Conversion of 5 to 6 is a

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