A 50 kg human is given an IV dose of 800 mg (16 mg/kg) of a chemical, and the plasma concentration of the chemical is plotted vs. time in the figures below.

3) What is the elimination halflife (t_1/2) of the chemical?

4) How long would it take to reach steady-state plasma levels if the chemical was given by chronic exposure?

16 8H Plasma drug concentration (mg/L) 4 2H 1 2 10 2 10 4 6 8 Time (hours) 4 6 8 Time (hours)