Question
A technique known as fluorescence recovery after photobleaching (FRAP) is used to measure the diffusivity of fluorescein (MW=332 Da), a fluorescent tracer, in the porcine
A technique known as fluorescence recovery after photobleaching (FRAP) is used to measure the diffusivity of fluorescein (MW=332 Da), a fluorescent tracer, in the porcine temporomandibular joint (TMJ) disk. The TMJ disk consists mostly of water and large a large amount of Type I collagen. The overall average diffusivity of fluorescein in the TMJ disk was found to be 57.0 m2/s. Use the Brinkman model to estimate the value of for the fluorescein diffusion in the porcine TMJ disk. Assume that the measurements were made at 37 "C" . (Ans: =11.963 nm^(-1))
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