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As with the Evans auxiliaries, the Davies auxiliaries can be prepared from the corresponding amino acid. Propose a strategy for the synthesis of the SuperQuat
As with the Evans auxiliaries, the Davies auxiliaries can be prepared from the corresponding
amino acid. Propose a strategy for the synthesis of the SuperQuat below from valine. For this question
it will be sufficient to work with synthons rather than specific reagents. In other words, I am interested
mostly in your retrosynthetic analysis.
Q3. Provide a mechanism for the conversion of the ketone at left to the product in the middle. Also, suggest a method (one or multiple steps) to convert the middle compound to the ketone at right. Your method should include reaction conditions (reagents, solvents, equivalents, etc.). NaoMe, Me Me Me H Me H OEt then Ac_0 OAC MeStep by Step Solution
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