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You are asked to prepare 1.2 L of 0.05M tris buffer with a pH: 7.8. You start with the conjugate base of tris (121 g/mol).

You are asked to prepare 1.2 L of 0.05M tris buffer with a pH: 7.8. You start with the conjugate base of tris (121 g/mol). How many grams of tris do you need? How many mL of 6M HCl (strong acid) do you need to add to reach pH:7.8? The pKa for tris is 8.1.

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