Question
You have carried out the below reaction between an acid chloride with an amine to form an amide. Construct a flow chart to show
You have carried out the below reaction between an acid chloride with an amine to form an amide. Construct a flow chart to show how you would isolate the product from unreacted starting materials using a reactive acid base extraction. Keep in mind that acid chlorides are readily hydrolyzed to carboxylic acids in the presence of aqueous acid or base, and that amides are not extracted into aqueous acid or base. Assume you have DCM, 1.0M HCl, 1.0M NaOH, and saturated NaHCO. CI+HN N CH2Cl2 excess
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Elements Of Chemical Reaction Engineering
Authors: H. Fogler
6th Edition
013548622X, 978-0135486221
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