The antibiotic paromomycin binds to a ribosome and induces the same conformational changes in 16S rRNA residues

Question:

The antibiotic paromomycin binds to a ribosome and induces the same conformational changes in 16S rRNA residues A1492 and A1493 as are induced by codon-anticodon pairing (Fig. 27-32). Propose an explanation for the antibiotic effect of paromomycin.

Fantastic news! We've Found the answer you've been seeking!

Step by Step Answer:

Related Book For book-img-for-question

Fundamentals of biochemistry Life at the Molecular Level

ISBN: 978-0470547847

4th edition

Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt

See More Books

Question Posted: Apr 30, 2016 02:58 PM

See More Questions

The antibiotic thiarubin-A was discovered by studying the feeding habits of wild chimpanzees in Tanzania. The structure for thiarubin-A is a. Complete the Lewis structures showing all lone pairs of...
The antibiotic oligomycin B blocks proton transport through F0. Explain why lactate concentrations build up in rats who have been treated with oligomycin B.
The antibiotic cordycepin inhibits bacterial RNA synthesis. (a) Of which nucleoside is cordycepin a derivative? (b) Explain cordycepin's mechanism of action. NH, N. HOCH O Cordycepin
Elizabeth Is a nurse, and she just administered 1.8 milliliters of medication to one of her patients. Elizabeth knows that the amount of medication remaining in the patient's body wi decrease by a...
Izzy is an employee of Kosmo's Kustom Kars, Inc. The company rebuilds classic automobiles for resale. Last year, Izzy bought a rebuilt 1956 Thunderbird for $15,000 from the company. A car like Izzy's...
Setting up and organizing a chart of accounts. (p. 42) LO.1
Find two possible mechanisms for the decay p + + e by suitably relabelling the lines in Figure 12.4(a) and (b). Check that the electric charge Q and the difference (B L) are both conserved at the...
During 2016, Rachael Parkins, president of Mathieson Company, was paid a semimonthly salary of $7,000. Compute the amount of FICA taxes that should be withheld from her: OASDI HI a. 9th paycheck b....
Required information [The following information applies to the questions displayed below.) Forten Company's current year income statement, comparative balance sheets, and additional information...
The following information is extracted from the statements of financial position of WestJet Airlines All amounts are in thousands of Canadian dollars Net earnings for the year ended December 31 2015...
When a sequence of deoxynucleotides is entered into a translation program (such as the ExPASy Translate tool at www.expasy.org/tools/dna.html), six possible polypeptide sequences are given as...
The rate of the peptidyl transferase reaction increases as the pH increases from 6 to 8. Explain these results in terms of its reaction mechanism.
What are the alternatives? LO-7
Evaluation a. Evaluate the effectiveness of social media marketing campaign for instagram, facebook and pintrest ?based on your KPIs for example account reached, content reached, likes, shares,...
A study was performed at a university to analyze whether the preference for hamburgers or fried chicken is related to the gender of the student. This table lists the results of the study. At a =...
A 20-lb homogeneous box has tipped and is resting against a 40-lb homogeneous box as shown in figure attached. The coefficient of friction between box A and the floor is 0.7, and between box B and...
The Taylor series for natural logarithm (with base e) In(1+r) is In(1+2) -(-1)+1 for <1. (a) Write a user-defined function using loop that determines In(1+x) using the above Taylor series. Your...
Question 1: [up to 4 pts] Suppose that a = 1, a2 = 2, a3 = = 3, and an = an-3 for all n 4. If an integral with respect to y is used to find the area of R, what should the upper limit of integration...
A single card is drawn from a standard 52-card deck. In Problems 714, find the conditional probability that The card is a heart, given that it is an ace.
What is your opinion of advertising awards, such as the Cannes Lions, that are based solely on creativity? If you were a marketer looking for an agency, would you take these creative awards into...
Provide an IUPAC name for each of the following alcohols: a. b. c. d. e. HO. Br Br
Mandelate esters exhibit spasmolytic activity (they act as muscle relaxants). The nature of the alkyl group (R) greatly affects potency. Research indicates that the optimal potency is achieved when R...
Draw the alkoxide formed in each of the following cases: a. b. c. d. HO ? Na NaH
Given that rJ = 6.3%, rRF = 4.1%, and rM = 9.4%, determine the beta coefficient for Stock J that is consistent with equilibrium.
Simon Companys year-end balance sheets follow. At December 31 2017 2016 2015 Assets Cash $ 33,019 $ 37,839 $ 38,623 Accounts receivable, net 93,822 65,556 54,152 Merchandise inventory 117,963 89,253...
PLEASE REFER TO THE 2018 ANNUAL REPORT OF STARBUKS FOR THE YEAR FISCAL YR 2018, ENDING SEPTEMBER 30, 2018. Refer to the management discussion & analysis section and write a one page summary...

The antibiotic paromomycin binds to a ribosome and induces the same conformational changes in 16S rRNA residues

Question:

C1054 G530 A1493 A1492 S12 C1054 tRNA G530 A1493 A1492 mRNA S12

Step by Step Answer:

By inducing the same conformational changes that occur during corre...View the full answer

Fundamentals of biochemistry Life at the Molecular Level

Students also viewed these Medical Sciences questions