Tranexamic acid, a drug useful against blood clotting, Is prepared commercially from p-methyl Benzonitrile. Formulate the steps

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Tranexamic acid, a drug useful against blood clotting, Is prepared commercially from p-methyl Benzonitrile. Formulate the steps likely to be used in the synthesis. (Don?t worry about cis-trans isomers; heating to 300 ?C interconvert?s the isomers.)

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Organic Chemistry

ISBN: 9780495112587

7 Edition

Authors: John McMurry

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Question Posted: Feb 28, 2011 04:55 AM

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Tranexamic acid, a drug useful against blood clotting, Is prepared commercially from p-methyl Benzonitrile. Formulate the steps

Question:

H. CO2H Tranexamic acid H2NCH2

Step by Step Answer:

OH NBS excess P PhCO22 NH3 CHBr CN CH3 H3O OH CH3 OH HOC H H RhC CHNH H CH2NH2 ...View the full answer

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