What is the rationale for administering a high dose of methotrexate followed by a massive amount of

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What is the rationale for administering a high dose of methotrexate followed by a massive amount of N5-formyltetrahydrofolate and thymidine to a cancer patient?
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Fundamentals of biochemistry Life at the Molecular Level

ISBN: 978-0470547847

4th edition

Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt

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