You have a 5 mL sample of a protein in 0.5 M NaCl. You place the protein/salt sample inside dialysis tubing and place the bag in a large beaker of distilled water. If your goal is to remove as much NaCl from the sample as possible, which would be more effective: (1) placing the dialysis bag in 4 L of distilled water for 12 h, or (2) placing the bag in 1 L of distilled water for 6 h and then in another 1 L of fresh distilled water for another 6 h?