Malate generated inside the mitochondrion is translocated to the cytosol, where it is a substrate for cytosolic

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Malate generated inside the mitochondrion is translocated to the cytosol, where it is a substrate for cytosolic malic enzyme, which catalyzes the following reaction:

Explain how the activity of malic enzyme, which appears to catalyze a catabolic process, can promote biosynthetic reactions in the cytosol.

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Fundamentals Of Biochemistry Life At The Molecular Level

ISBN: 9781118918401

5th Edition

Authors: Donald Voet, Judith G Voet, Charlotte W Pratt

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Question Posted: Oct 04, 2023 07:23 AM

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Malate generated inside the mitochondrion is translocated to the cytosol, where it is a substrate for cytosolic

Question:

malate + NADP+ CO + pyruvate + NADPH

Step by Step Answer:

Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate CO2 and NADPH This reacti...View the full answer

Fundamentals Of Biochemistry Life At The Molecular Level

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