Many drugs function by interfering with metabolic pathways. The anticancer drug methotrexate, for instance, inhibits the dihydrofolate
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Many drugs function by interfering with metabolic pathways. The anticancer drug methotrexate, for instance, inhibits the dihydrofolate reductase enzyme that catalyzes the following reactions:
What cofactor is likely to be involved in these reductions? Propose a mechanism.
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The likely cofactor involved in the reductions catalyzed by the dihydrofolate reductase enzyme is NA...View the full answer
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Abdul Wahab Qaiser
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